Method Comparison Table

Parameter	PRP	CGF	BMAC	Lipogems/SVF
Source	Blood (15-30 ml)	Blood (20-40 ml)	Bone marrow (60 ml)	Fat tissue (30-60 ml)
MSC content	Minimal (~0)	Minimal	2-5 million	15-20 million
Growth factors	PDGF, TGF-b, VEGF	PDGF, TGF-b, VEGF, BMP	BMP, FGF, PDGF	VEGF, FGF, HGF, NGF
Fibrin scaffold	No	Yes (3D matrix)	No	Yes (stroma)
Anesthesia	None	None	Local	Local
Procedure time	30 min	45 min	60 min	90 min
Sessions needed	3-5	1-2	1	1
Effect duration	6-12 months	1-3 years	2-4 years	2-5 years
Indications	OA grade 1-2	OA grade 1-3, discs	OA grade 2-3, AVN	OA grade 2-4, FBSS
Cost	500-1500 EUR x3-5	from 7500 EUR	from 7500 EUR	from 9500 EUR

Which Method to Choose?

PRP — Entry Level

Best for: tendinopathies under 6 months, grade 1-2 osteoarthritis, fresh ligament injuries. No stem cells, needs repeated courses, ineffective at advanced stages.

CGF — Advanced Level

Best for: grade 2-3 osteoarthritis, disc degeneration (Pfirrmann II-III), chronic tendinopathies. 3D fibrin scaffold holds growth factors in the injection zone for 7-14 days.

BMAC — Bone Marrow Stem Cells

Best for: avascular necrosis, bone marrow edema, grade 2-3 OA with subchondral changes. High concentration of hematopoietic and mesenchymal cells plus BMP.

Lipogems/SVF — Maximum Power

Best for: grade 3-4 osteoarthritis, FBSS, multiple affected areas, PRP failure. Maximum MSC concentration (15-20 million), preserved stroma, immunomodulatory effect.

MIBRAR — Combined Protocol

At MIBRAR we don't rely on a single method. The protocol is tailored individually and often combines: CGF + Lipogems for joints, CGF + BMAC for spine. This ensures synergistic effect and maximum regeneration.

Frequently Asked Questions

What is the difference between SVF and PRP?

PRP contains only platelets and growth factors from blood. SVF contains mesenchymal stem cells from adipose tissue — MSC concentration is 100-500x higher.

When is PRP sufficient?

PRP works for early stages (grade 1-2 OA, acute tendinopathies). For grade 3+ OA and chronic damage, stem cells are needed.

SVF vs Lipogems — which is better?

SVF yields more cells but requires enzymatic processing. Lipogems uses mechanical processing, preserves cell niche, fully EU-legal.

How much does each method cost?

PRP: 500-1500 EUR x 3-5 sessions. CGF/BMAC: from 7500 EUR (single). Lipogems: from 9500 EUR (single).

Not Sure Which Method Is Right?

Send your MRI — we'll determine the optimal treatment protocol for your case, free of charge.

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