What is PRP therapy

PRP (Platelet-Rich Plasma) is blood plasma with an increased platelet concentration. Platelets store alpha-granules — a depot of growth factors: PDGF, TGF-β, VEGF, EGF, IGF-1, bFGF. Once activated, platelets release these proteins that:

Stimulate cell division

Chondrocytes (cartilage), tenocytes (tendons), fibroblasts (ligaments) all respond to growth factors by proliferating and synthesizing matrix.

Improve blood supply

VEGF stimulates formation of new microvessels. Critical for tendons — they have poor baseline blood supply.

Modulate inflammation

PRP shifts chronic non-productive inflammation to acute regenerative. The tissue remodels and heals instead of slowly degrading.

Trigger collagen production

Regenerated ligaments and tendons restore their collagen fiber structure — visible on post-treatment ultrasound.

When PRP is used

Stage I–II arthrosis

Knee (gonarthrosis), shoulder (omarthrosis), hip (coxarthrosis), ankle, hand joints. At stage I–II, PRP is an optimal choice for cartilage regeneration.

Tendinopathies

Tennis and golfer's elbow, Achilles tendinopathy, plantar fasciitis, patellar tendinopathy, rotator cuff tendinopathy, de Quervain's.

Ligament and meniscus injuries

Partial ACL, PCL and collateral ligament tears. Degenerative and stable meniscal tears. Combined with orthopedic immobilization.

Sports trauma

Muscle tears, hamstring strains, Hoffa pad injuries, bone marrow bruises. PRP accelerates return to sport by 20–40%.

Spine

Early degenerative disc disease, facet syndrome, myofascial trigger points. Targeted injections under ultrasound guidance.

Post-surgical recovery

Accelerated healing after arthroscopy, ligament reconstruction. PRP complements orthopedic care.

PRP vs CGF vs Lipogems®

PRP

The most accessible product. Easy harvest (venous blood), minimal invasiveness. Optimal for mild and moderate degeneration, sports injuries. Effect lasts 6–12 months; courses can be repeated.

CGF (Concentrated Growth Factors)

Evolution of PRP. Higher growth factor concentration in a fibrin matrix. Longer and stronger effect. Indicated for moderate and severe stages, chronic tendinopathies.

Lipogems® Ortho / SVF / BMAC

Cellular products — mesenchymal cells from fat or bone marrow. Used for severe arthrosis, large cartilage defects, failed back surgery. Maximum regenerative potential.

Product choice is the physician's task after MRI and exam. A combination is often used — for example, Lipogems® + CGF in one visit.

How the procedure works

1. Blood draw

10–30 mL from a vein — like a routine blood test. Takes 2–3 minutes.

2. Centrifugation

A standardized centrifugation protocol separates blood into fractions. Platelet-rich plasma is collected. 10–15 minutes.

3. Ultrasound navigation

The doctor marks the injection point under ultrasound. Sono-Control Arm fixes the probe; Cyber-Navi-Hand tracks needle position.

4. Injection

Local anesthesia. PRP is placed precisely into the damage zone. 10–15 minutes. Practically painless.

5. Observation

30–60 minutes post-procedure in the clinic. No hospitalization needed.

6. Home the same day

Return to light activity — immediately. Return to sport — in 1–2 weeks (by doctor's approval).

Results and timing

2–3Sessions per course
2–4 wkInterval between sessions
3 moPeak effect
12+ moDuration of effect

In the first 1–3 days, mild tenderness and swelling are possible — part of the regenerative response. NSAIDs are not recommended during this period (they suppress regeneration). Warm compresses and rest are enough.

Find out if PRP is right for your case

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Frequently asked questions

What is PRP therapy?

Autologous plasma enriched with platelets and growth factors. Injected into damaged tissue for regeneration.

What conditions does PRP treat?

Stage I–II arthrosis, tendinopathies, ligaments, meniscus, sports injuries, early disc degeneration.

How does MIBRAR® PRP differ?

Standardized protocol, ultrasound and optical navigation, individualized plan, often with CGF/Lipogems®, MRI monitoring.

How many procedures are needed?

Usually 2–3 with a 2–4 week interval. For severe degeneration — up to 4–5 or combined with CGF.

Are there side effects?

Local tenderness 1–3 days — normal. No immune rejection (own material). Serious complications are extremely rare.