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Video about the MIBRAR® Method
Video: Reconstruction of Intervertebral Discs
What is disc protrusion
Disc protrusion is a bulging of the intervertebral disc beyond its anatomical boundaries while the annulus fibrosus remains intact. This is an intermediate stage between a normal disc and a herniation. If the annulus fibrosus ruptures, the protrusion becomes a herniated disc.
Stages of disc degeneration
1. Disc dehydration
The nucleus pulposus loses water, reducing disc height. On MRI, there is signal loss in T2 mode (disc appears dark). Symptoms are minimal: occasional morning stiffness.
2. Protrusion
The weakened annulus fibrosus cannot withstand load, and the disc bulges outward. Protrusion size: 1-5 mm. May compress nerve roots, causing pain, numbness, and weakness. This is the optimal stage for MIBRAR® treatment — the annulus fibrosus can still be restored.
3. Extrusion (herniation)
The annulus fibrosus ruptures, and the nucleus pulposus extends outward. Size typically 5-12 mm. More pronounced nerve compression. MIBRAR® is effective at this stage as well, but treating protrusion is simpler with better results.
4. Sequestration
A fragment of the herniation detaches and migrates into the epidural space. The most complex stage, but even here MIBRAR® can be effective when combined with anti-inflammatory therapy.
Location of protrusions
Lumbar spine (90%)
L4-L5 — the most common location. Low back pain, radiation along the outer surface of the thigh and leg, numbness of the big toe.
L5-S1 — the second most common. Pain along the back of the leg, numbness of the little toe, weakness of plantar flexion.
L3-L4 — pain along the front of the thigh, weakness of knee extension.
Cervical spine (8%)
C5-C6 — numbness of the thumb and index finger, biceps weakness.
C6-C7 — numbness of the middle finger, triceps weakness. Cervical protrusions are more dangerous than lumbar ones due to proximity to the spinal cord.
Thoracic spine (2%)
Rare location. Chest pain, intercostal neuralgia. Often misdiagnosed as a cardiac problem.
Symptoms of protrusion
Local pain
Dull, aching pain in the affected segment. Worsens after prolonged sitting, bending, lifting heavy objects. Improves when lying down.
Radicular pain
When a nerve root is compressed — shooting pain along the nerve pathway (down the leg with lumbar protrusion, down the arm with cervical protrusion). Worsens with coughing or sneezing.
Numbness and Paresthesias
Tingling, "pins and needles," reduced sensation in the innervation zone of the compressed nerve root. Key symptom—indicates nerve compression.
Muscle Weakness
With prolonged compression—weakness in specific muscle groups. Sign of serious nerve damage requiring urgent treatment.
Why disc protrusion must be treated now
Disc protrusion is a window of opportunity. At this stage, the fibrous ring is still intact and amenable to regeneration. Without treatment:
Progression to Herniation
70% of untreated protrusions progress to herniation within 3-5 years if risk factors persist.
Chronic Pain
Prolonged nerve compression leads to central sensitization—pain becomes chronic and difficult to treat.
Irreversible Nerve Damage
Compression lasting more than 6-12 months can cause demyelination and axonal degeneration—numbness and weakness become permanent.
Treatment of Disc Protrusion Using the MIBRAR® Method
MIBRAR® is the only method capable of restoring the structure of the intervertebral disc at the cellular level.
1. MRI Analysis
Prof. Babayan assesses: size and direction of the protrusion, condition of the fibrous ring, degree of compression of neural structures, presence of Modic changes in the endplates.
2. Biomaterial Preparation
CGF from patient's blood (growth factors, fibrin matrix) + Lipogems® from mini-lipoaspirate (mesenchymal stem cells, pericytes, extracellular matrix).
3. Intradiscal Injection
Under Cyber Navi Hand™ and C-arm guidance, the needle is positioned in the center of the damaged disc (accuracy 0.1 mm). Biomaterials are injected directly into the weakened fibrous ring and dehydrated nucleus pulposus.
4. Regeneration
Stem cells differentiate into fibrochondrocytes, restoring the collagen structure of the fibrous ring. CGF stimulates proteoglycan synthesis, restoring nucleus hydration. Follow-up MRI at 6-12 months shows restoration of disc T2 signal.
Disc Protrusion—The Best Time for Treatment
Don't wait for it to become a herniation. Send your MRI for free evaluation.
Send MRI ImagesTreatment Results for Disc Protrusion
Follow-up MRI scans demonstrate fibrous ring regeneration and protrusion reduction after the MIBRAR® procedure.
WGZM Case: regeneration dynamics
Diagnosis: thoracic disc protrusions. 6 MRI images (3 sagittal + 3 axial) show dynamics: before → 7 weeks → 16 weeks after MIBRAR®.
Result: progressive protrusion reduction, fibrous ring strengthening, disc height restoration. Progression to herniation prevented.
View case study →
WGZM Case: female, 54 years
Diagnosis: massive central protrusion L5/S1 measuring 14 mm, progressing to herniation. Sagittal MRI with measurements — right leg paraparesis.
Result at 11 months: protrusion regression, disc contour restoration, nerve structure decompression. Full sports activity at 6 weeks.
View case study →Questions About Disc Protrusion
In protrusion, the disc's fibrous ring is still intact—the disc bulges but does not rupture. In herniation, the ring ruptures and the nucleus extrudes. Protrusion is the precursor stage to herniation and the optimal time for treatment.
No. Without treatment, protrusion stabilizes or progresses. Spontaneous disc restoration does not occur—adult discs have virtually no blood supply. MIBRAR® delivers regenerative factors directly into the disc.
In the vast majority of cases—no. Surgical indications for protrusion are extremely rare (cauda equina syndrome, progressive paresis). MIBRAR® is the optimal method for protrusions: regenerates the disc without surgery.
The cost depends on the number of affected discs and associated pathology. For an exact calculation, send MRI images via the website form—consultation is free.
Swimming, walking, yoga — beneficial. Running, jumping, heavy lifting — restrict until treatment. After MIBRAR® — full sports activity in 4-6 weeks. Core muscle strengthening — mandatory for recurrence prevention.